Lucy is a 25-year-old American woman living and studying in Taipei, Taiwan. She is tricked into working as a drug mule by her new boyfriend, whose employer, Mr. Jang, is a Korean mob boss and drug lord. Lucy delivers a briefcase to Mr. Jang containing a highly valuable synthetic drug called CPH4. After seeing her boyfriend shot and killed, she is captured and a bag of the drug is forcibly sewn into her abdomen and that of three other drug mules who will also transport the drug for sales in Europe.
While Lucy is in captivity, one of her captors kicks her in the abdomen, breaking the bag, releasing a large quantity of the drug into her system. As a result, she begins acquiring increasingly enhanced physical and mental capabilities, such as telepathy, telekinesis, mental time travel, and can choose not to feel pain or other discomforts, in addition to other abilities. She kills off her captors and escapes.
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